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Unha oportunidade magnífica para falar de todo un pouco, de gaitas e de xenes. Co magnífico Pablo Carpintero, músico, lutier, biólogo, etc... un libro aberto. E que mellor que na compañía de Manuel Vicente e Cesar Goldi. Un placer!

TVG en directo | CRTVG

IntroductionThe relationship between music and Alzheimer’s disease (AD) has been approached by different disciplines, but most of our outstanding comes from neuroscience.MethodsFirst, we systematically reviewed the state-of-the-art of neuroscience and cognitive sciences research on music and AD (>100 studies), and the progress made on the therapeutic impact of music stimuli in memory. Next, we meta-analyzed transcriptomic and epigenomic data of AD patients to search for commonalities with genes and pathways previously connected to music in genome association, epigenetic, and gene expression studies.ResultsOur findings indicate that >93% of the neuroscience/ cognitive sciences studies indicate at least one beneficial effect of music on patients with neurodegenerative diseases, being improvements on memory and cognition the most frequent outcomes; other common benefits were on social behavior, mood and emotion, anxiety and agitation, quality of life, and depression. Out of the 334 music-related genes, 127 (38%) were found to be linked to epigenome/transcriptome analysis in AD (vs. healthy controls); some of them (SNCA, SLC6A4, ASCC2, FTH1, PLAUR and ARHGAP26) have been reported to be associated e.g. with musical aptitude and music effect on the transcriptome. Other music-related genes (GMPR, SELENBP1 and ADIPOR1) associated to neuropsychiatric, neurodegenerative diseases and music performance, emerged as hub genes in consensus co-expression modules detected between AD and mu...

We really enjoyed to share the time with the children! Nice opportunity to explain future researchers how research works! They had the opportunity to extract DNA from strawberries, pipetting, etc.

Music has an impact on mood. But what about the genes? There are key hymns, they make our hair stand on end, others fill us with melancholy and we even cry, and...